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Polyphosphazenes
Polydichlorophosphazene
Polydichlorophosphazene (PDCP) is one of our key products. Our proprietary methods allow us to
synthesize linear polydichlorophosphazene. By using the methods, the molecular weight of PDCP can be
well controlled, and also narrow polydispersity can be obtained. Upon customer's request, PDCP with
different molecular weights, from 1 K to 500 K, can be synthesized in either grams scale or tens of
kilograms scale in our lab.
Polyphosphazenes
PDCP is a key intermediate for access to a broad range of phosphazene polymers. As shown in the
following scheme, through nucleophilic substitution approaches, various polyphosphazenes can be
synthesized from PDCP.
Substituents (see the list below for some examples) may largely determine the properties of
polyphosphazenes, e.g., hydrophobicity or hydrophilicity, glass transition temperature (Tg), etc. This
feature plus the biodegradable backbone chain makes polyphosphazenes uniquely useful in drug release
or delivery systems, biomedical devices, membrane or hydrogel systems, etc.
With our expertise in this field, we can provide you technical support in design and synthesis of various
phosphazene polymers. Also please click here to see our phosphazene polymer products.
Some examples of nucleophilic substitional groups (-R) :
-Alkyl groups
-Alkenyl groups
-Fluoro groups, e.g., -CH2CF3, -C(CH3)2CF3, -C(CF3)C6H5, etc.
-Aryl groups, e.g., -C6H5, -C6H4R’, -C6H4NH2, -C6H4COOH, -C6H4COH, -C6H4OMe,
-C6H4SO3H, -CH2C6H5, etc.
-Amine groups, e.g., -R'NH2
-PEG groups, e.g., -PEG-OMe
Others, e.g., -R’NHC3H6SO3H, -CHR’COOR”, -CH2CONHCOOR”, -CHR’COOCHCOOR”
Polydichlorophosphazene
Polydichlorophosphazene (PDCP) is one of our key products. Our proprietary methods allow us to
synthesize linear polydichlorophosphazene. By using the methods, the molecular weight of PDCP can be
well controlled, and also narrow polydispersity can be obtained. Upon customer's request, PDCP with
different molecular weights, from 1 K to 500 K, can be synthesized in either grams scale or tens of
kilograms scale in our lab.
Polyphosphazenes
PDCP is a key intermediate for access to a broad range of phosphazene polymers. As shown in the
following scheme, through nucleophilic substitution approaches, various polyphosphazenes can be
synthesized from PDCP.
Substituents (see the list below for some examples) may largely determine the properties of
polyphosphazenes, e.g., hydrophobicity or hydrophilicity, glass transition temperature (Tg), etc. This
feature plus the biodegradable backbone chain makes polyphosphazenes uniquely useful in drug release
or delivery systems, biomedical devices, membrane or hydrogel systems, etc.
With our expertise in this field, we can provide you technical support in design and synthesis of various
phosphazene polymers. Also please click here to see our phosphazene polymer products.
Some examples of nucleophilic substitional groups (-R) :
-Alkyl groups
-Alkenyl groups
-Fluoro groups, e.g., -CH2CF3, -C(CH3)2CF3, -C(CF3)C6H5, etc.
-Aryl groups, e.g., -C6H5, -C6H4R’, -C6H4NH2, -C6H4COOH, -C6H4COH, -C6H4OMe,
-C6H4SO3H, -CH2C6H5, etc.
-Amine groups, e.g., -R'NH2
-PEG groups, e.g., -PEG-OMe
Others, e.g., -R’NHC3H6SO3H, -CHR’COOR”, -CH2CONHCOOR”, -CHR’COOCHCOOR”
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| CM-Tec, Inc., Email: info@cmtec-inc.com |