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Polyphosphazenes
Polydichlorophosphazene
Polydichlorophosphazene (PDCP) is one of our key products. Our proprietary methods allow
us to synthesize linear polydichlorophosphazene. By using the methods, the molecular
weight of PDCP can be well controlled, and also narrow polydispersity can be obtained. Upon
customer's request, PDCP with different molecular weights, from 1 K to 500 K, can be
synthesized in either grams scale or tens of kilograms scale in our lab.
Polyphosphazenes
PDCP is a key intermediate for access to a broad range of phosphazene polymers. As shown
in the following scheme, through nucleophilic substitution approaches, various
polyphosphazenes can be synthesized from PDCP.
Substituents (see the list below for some examples) may largely determine the properties of
polyphosphazenes, e.g., hydrophobicity or hydrophilicity, glass transition temperature (Tg),
etc. This feature plus the biodegradable backbone chain makes polyphosphazenes uniquely
useful in drug release or delivery systems, biomedical devices, membrane or hydrogel
systems, etc.
With our expertise in this field, we can provide you technical support in design and synthesis
of various phosphazene polymers. Also please click here to see our phosphazene polymer
products.
Some examples of nucleophilic substitional groups (-R) :
-Alkyl groups
-Alkenyl groups
-Fluoro groups, e.g., -CH2CF3, -C(CH3)2CF3, -C(CF3)C6H5, etc.
-Aryl groups, e.g., -C6H5, -C6H4R’, -C6H4NH2, -C6H4COOH, -C6H4COH, -C6H4OMe,
-C6H4SO3H, -CH2C6H5, etc.
-Amine groups, e.g., -R'NH2
-PEG groups, e.g., -PEG-OMe
Others, e.g., -R’NHC3H6SO3H, -CHR’COOR”, -CH2CONHCOOR”, -CHR’COOCHCOOR”
Polydichlorophosphazene
Polydichlorophosphazene (PDCP) is one of our key products. Our proprietary methods allow
us to synthesize linear polydichlorophosphazene. By using the methods, the molecular
weight of PDCP can be well controlled, and also narrow polydispersity can be obtained. Upon
customer's request, PDCP with different molecular weights, from 1 K to 500 K, can be
synthesized in either grams scale or tens of kilograms scale in our lab.
Polyphosphazenes
PDCP is a key intermediate for access to a broad range of phosphazene polymers. As shown
in the following scheme, through nucleophilic substitution approaches, various
polyphosphazenes can be synthesized from PDCP.
Substituents (see the list below for some examples) may largely determine the properties of
polyphosphazenes, e.g., hydrophobicity or hydrophilicity, glass transition temperature (Tg),
etc. This feature plus the biodegradable backbone chain makes polyphosphazenes uniquely
useful in drug release or delivery systems, biomedical devices, membrane or hydrogel
systems, etc.
With our expertise in this field, we can provide you technical support in design and synthesis
of various phosphazene polymers. Also please click here to see our phosphazene polymer
products.
Some examples of nucleophilic substitional groups (-R) :
-Alkyl groups
-Alkenyl groups
-Fluoro groups, e.g., -CH2CF3, -C(CH3)2CF3, -C(CF3)C6H5, etc.
-Aryl groups, e.g., -C6H5, -C6H4R’, -C6H4NH2, -C6H4COOH, -C6H4COH, -C6H4OMe,
-C6H4SO3H, -CH2C6H5, etc.
-Amine groups, e.g., -R'NH2
-PEG groups, e.g., -PEG-OMe
Others, e.g., -R’NHC3H6SO3H, -CHR’COOR”, -CH2CONHCOOR”, -CHR’COOCHCOOR”
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